N-formylation of amine using graphene oxide as a sole recyclable metal-free carbocatalyst

作者：Ma, Juan; Zhang, Jingyu; Zhou, Xiao; Wang, Jiawei; Gong, Hang^*

来源：Journal of the Iranian Chemical Society, 2018, 15(12): 2851-2860.

DOI：10.1007/s13738-018-1471-3

• Synthetic methodology
• Graphene oxide
• Hydroformylation
• C-N bond formation
• Recyclability

Graphene oxide (GO), an inexpensive, environment-friendly, and metal-free carbocatalyst, used for the N-formylation of amines is developed. In this reaction, GO shows good activity, selectivity, and recyclability. This strategy has an array of advantages, such as being metal free, without additive, wide-scope protocol, scalable with a low catalyst loading of 3wt%, use of readily available and recyclable carbocatalyst, and DMF as a readily available formyl source. Furthermore, this strategy provides an avenue for the convenient hydroformylation of various amines.
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• 出版日期2018-12
• 单位湘潭大学