Sexual function after treatment for sacrococcygeal teratoma during childhood

作者：Kremer Marijke E B; Derikx Joep P M; Peeters Andrea; ter Kuile Moniek M; van Baren Robertine; Heij Hugo A; Wijnen Marc H W A; Wijnen Rene M H; van der Zee David C; van Heurn L W Ernest^*

来源：Journal of Pediatric Surgery, 2016, 51(4): 534-540.

DOI：10.1016/j.jpedsurg.2015.09.013

• Germ cell tumor
• Sexual function
• Sequelae

Background: Children treated for sacrococcygeal teratoma (SCT) may suffer from sexual dysfunction later in life because of the extended pelvic surgery performed, however, structured evaluations have not been performed yet.
Methods: The Female Sexual Function Index (FSFI), the International Index of Erectile IIEF) and the Body Image Questionnaire (BIQ) were sent to patients (>= 18 years) treated for SCT in the Dutch pediatric surgical centers after 1970.
Results: Forty-five of 76 patients returned the questionnaires; 28 women (median age 27.3 years, range 18.3-41.0) and seven men (median age 22.0 years, range 19.1-36.5) were eligible for analysis. The FSFI and IIEF results were compared to healthy controls. Female patients scored significantly lower on the desire (p=0.014), arousal (p=0.013) and lubrication domain (p=0.019). FSFI total-scores of female patients were significantly lower compared to controls [median 30.5 (IQR 28.6-31.4) vs. median 32.4 (IQR 30.6-33.45) p <= 0.001] but were above the threshold value for sexual dysfunction. Males reported normal erectile function and penetration ability with normal ejaculation. Females had significant lower BIQ results compared to males; BIQ-cosmesis scores were moderately correlated to the FSFI-desire score (r= -0.37, p = 0.028).
Conclusion: SCT resection in girls may result in diminished sexual function at adult age with worse self-perceived body image. The possibility of sexual complaints should be integrated in the surveillance strategies for these patients.

• 出版日期2016-4