Arabidopsis BTB/POZ protein-dependent PENETRATION3 trafficking and disease susceptibility

作者：Mao Hailiang; Aryal Bibek; Langenecker Tobias; Hagmann Jorg; Geisler Markus; Grebe Markus^*

来源：Nature Plants, 2017, 3(11): 854-858.

DOI：10.1038/s41477-017-0039-z

The outermost cell layer of plant roots (epidermis) constantly encounters environmental challenges. The epidermal outer plasma membrane domain harbours the PENETRATION3 (PEN3)/ABCG36/PDR8 ATP-binding cassette transporter that confers non-host resistance to several pathogens. Here, we show that the Arabidopsis ENDOPLASMIC RETICULUM-ARRESTED PEN3 (EAP3) BTB/POZ-domain protein specifically mediates PEN3 exit from the endoplasmic reticulum and confers resistance to a root-penetrating fungus, providing prime evidence for BTB/POZ-domain protein-dependent membrane trafficking underlying disease resistance.

• 出版日期2017-11