A new series of emodin derivatives with bone affinity

作者：Chen Hong^*; Wang Ying; Leng Ling; Cheng Mao Sheng; Yu Peng Fei; Zhang Jing Ze

来源：Chinese Chemical Letters, 2007, 18(2): 141-144.

DOI：10.1016/j.cclet.2006.12.021

• emodin
• 5-fluorouracil
• bone affinity
• antitumor

A new series of bone affinity compounds were synthesized by linking emodin with 5-fluorouracil derivatives. Their bone affinities were established by hydroxyapative (HA) affinity experiment in vitro, and their cytostatic effects were shown by the MTT assay.

• 出版日期2007-2
• 单位沈阳药科大学; 中国人民武装警察部队后勤学院