A diastereomerically enriched, dimeric organolithium compound and the stereochemical course of its transformations

作者：Unkelbach Christian; Abele Bors C; Lehmen Klaus; Schildbach Daniel; Waerder Benedikt; Wild Kerstin; Strohmann Carsten^*

来源：Chemical Communications, 2012, 48(19): 2492-2494.

DOI：10.1039/c1cc15872d

A dimeric alpha-silylated ethyllithium compound is presented featuring stereogenic metalated carbon centres with defined configurations. It can be generated by diastereoselective deprotonation of the corresponding ethylsilane. Reaction with Me3SnCl proceeds under inversion and the transfer of the stereoinformation is possible with dr%26apos;s of up to 97 : 3.

• 出版日期2012