Artificial Neural Network Approach in Laboratory Test Reporting Learning Algorithms

作者：Demirci Ferhat^*; Akan Pinar; Kume Tuncay; Sisman Ali Riza; Erbayraktar Zubeyde; Sevinc Suleyman

来源：American Journal of Clinical Pathology, 2016, 146(2): 227-237.

DOI：10.1093/AJCP/AQW104

• Neural networks (computer)
• Machine learning
• Biochemistry
• Clinical laboratory
• Information systems
• Autoverification

Objectives: In the field of laboratory medicine, minimizing errors and establishing standardization is only possible by predefined processes. The aim of this study was to build an experimental decision algorithm model open to improvement that would efficiently and rapidly evaluate the results of biochemical tests with critical values by evaluating multiple factors concurrently.
Methods: The experimental model was built by Weka software (Weka, Waikato, New Zealand) based on the artificial neural network method. Data were received from Dokuz Eylul University Central Laboratory. "Training sets" were developed for our experimental model to teach the evaluation criteria. After training the system, "test sets" developed for different conditions were used to statistically assess the validity of the model.
Results: After developing the decision algorithm with three iterations of training, no result was verified that was refused by the laboratory specialist. The sensitivity of the model was 91% and specificity was 100%. The estimated K score was 0.950.
Conclusions: This is the first study based on an artificial neural network to build an experimental assessment and decision algorithm model. By integrating our trained algorithm model into a laboratory information system, it may be possible to reduce employees' workload without compromising patient safety.

• 出版日期2016-8