ANTIOXIDANTAND IMMUNE-STIMULATING ACTIVITIES OF HOT-WATER EXTRACT FROM SEAWEED SARGASSUM HEMIPHYLLUM

作者：Hwang Pai An^*; Wu Chwen Herng; Gau Shu Yun; Chien Shih Yung; Hwang Deng Fwu

来源：Journal of Marine Science and Technology-Taiwan, 2010, 18(1): 41-46.

DOI：10.51400/2709-6998.1863

• sargassum hemiphyllum
• antioxidant activity
• HB4C5 cells
• J774.1 cells

The hot-water extract of seaweed Sargassunz hemiphyllum was evaluated antioxidant activity by using four different methods. including DPPH free radicals scavenging activity, Fe+2 chelating activity, superoxide anion radical scavenging activity and reducing power, and the immune-stimulating activity by using HB4C5 cells and J774.1 cells. It was found that the antioxidant activity was increasing in correlating with the concentration below 3.5 mg/ml. The HB4C5 cells showed the maximum relative activities of cell proliferation (174%) and IgM secretion (132%) at 120 mu g/ml of hot-water extract. Overheating slightly reduced the immune-stimulating activity of hot-water extract. At 80 mu g/ml. J774.1 cells showed the maximum relative activities of cell proliferation (141%) and phagocytosis (147%). Hence, the hot-water extract of seaweed S. hemiphyllum plays the important role on antioxidant and immune-stimulating activities.

• 出版日期2010-2