科研之友
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摘要
The direct sp(3) C-H bond functionalization of 2-alkyl azaarenes to isatylidene malononitriles has been achieved using Bi(OTf)(3) as the catalyst, resulting in a series of oxindoles containing an all-carbon quaternary center in moderate to good yields. This protocol provided an efficient and convenient method for the construction of potentially useful azaarene substituted oxindoles.
