Nosocomial Infections and Multidrug-Resistant Bacterial Organisms in the Pediatric Intensive Care Unit

作者：McGrath Eric J^*; Asmar Basim I

来源：Indian Journal of Pediatrics, 2011, 78(2): 176-184.

DOI：10.1007/s12098-010-0253-4

• Nosocomial infection
• PICU
• Multidrug resistant
• Bacterial
• Prevention

Nosocomial infections in Pediatric Intensive Care Units (PICUs) caused by multidrug-resistant bacterial organisms are increasing. This review attempts to report on significant findings in the current literature related to nosocomial infections in PICU settings with an international perspective. The types of nosocomial infections are addressed, including catheter-related bloodstream infections, ventilator-associated pneumonia, urinary tract infections, gastrointestinal infections and post-surgical wound infections. A review of emerging resistant bacterial pathogens includes methicillin-resistant Staphylococcus aureus, vancomycin-resistant Enterococcus sp., Clostridium difficile, extended-spectrum beta-lactamase producing Gram-negative organisms, Klebsiella pneumoniae carbapenemase-producing strains and multidrug resistant Acinetobacter baumannii. Basic and enhanced infection control methods for the management and control of multidrug-resistant organisms are also summarized with an emphasis on prevention.

• 出版日期2011-2