Health effects of diesel exhaust: A state of the art

作者：Habert C^*; Garnier R

来源：Revue des Maladies Respiratoires, 2015, 32(2): 138-154.

DOI：10.1016/j.rmr.2014.07.012

• Vehicle emissions
• Particulate matter
• Lung cancer
• Asthma Summary Introduction

Introduction. - This review presents the state of knowledge regarding the acute and chronic toxicity of diesel engine exhaust in humans.
State of art. - The health effects of diesel engine exhaust, which is a complex mixture of gas and particulate matter (ultrafine and fine particles), are mainly irritation of the respiratory tract and carcinogenicity. They may also facilitate the development of respiratory allergies. A recent reassessment by the International Agency for Research on Cancer concluded that there is sufficient evidence of a causal association between exposure to diesel engine exhaust and lung cancer.
Perspectives. - The epidemiologic data collected during the last two decades also show limited evidence of increased risks of bladder cancer, as well as of chronic obstructive pulmonary disease in diesel engine exhaust exposed workers. Both experimental and epidemiological studies have involved the effect of emissions from traditional diesel engine technology. Major developments in this technology have occurred recently and the toxicity of emissions from these new engines is still to be characterized.
Conclusion. - Further studies are needed to explore the link between diesel engine exhaust exposure and the risks of bladder cancer, as well as of chronic obstructive pulmonary disease and respiratory allergies. Research is also needed to get more information about the toxicity of the new diesel technology emissions.

• 出版日期2015-2