A mild CuI-catalyzed Glaser-type homo-coupling reaction using alpha,alpha-dibromo-beta-dicarbonyl compounds as oxidants

作者：Fan Xiaohui^*; Li Na; Shen Tong; Cui Xiao Meng; Lv Hao; Zhu Hong Bo; Guan Yong Hong

来源：Tetrahedron, 2014, 70(2): 256-261.

DOI：10.1016/j.tet.2013.11.076

• Glaser reaction
• Coupling reaction
• alpha,alpha-Dibromo-beta-dicarbonyl compound
• 1,3-Diyne
• Copper

Exploration of alpha,alpha-dibromo-beta-dicarbonyl compounds as novel organic oxidants for the mild Cu(I)-catalyzed Glaser-type homo-coupling reaction has been achieved, which provides an alternatively efficient pathway for the construction of 1,3-conjugated structures. In addition, the mechanism of this reaction was investigated.

• 出版日期2014-1-14
• 单位兰州交通大学