Emerging frontiers in detection and control of bacterial biofilms

作者：Tan Seth Yang En; Chew Su Chuen; Tan Sean Yang Yi; Givskov Michael; Yang Liang^*

来源：Current Opinion in Biotechnology, 2014, 26: 1-6.

DOI：10.1016/j.copbio.2013.08.002

Bacteria form surface-attached biofilm communities in nature. In contrast to free-living cells, bacterial cells within biofilms resist sanitizers and antimicrobials. While building biofilms, cells physiologically adapt to sustain the otherwise lethal impacts of a variety of environmental stress conditions. In this development, the production and embedding of cells in extracellular polymeric substances plays a key role. Biofilm bacteria can cause a range of problems to food processing including reduced heat-cold transfer, clogging water pipelines, food spoilage and they may cause infections among consumers. Recent biofilm investigations with the aim of potential control approaches include a combination of bacterial genetics, systems biology, materials and mechanic engineering and chemical biology.

• 出版日期2014-4