The Effectiveness of Web-Based Tools for Improving Blood Glucose Control in Patients with Diabetes Mellitus: A Meta-Analysis

作者：Angeles Ricardo N^*; Howard Michelle I; Dolovich Lisa

来源：Canadian Journal of Diabetes, 2011, 35(4): 344-352.

DOI：10.1016/S1499-2671(11)54011-0

• blood glucose control
• diabetes mellitus
• Internet-based intervention
• web-based tools

OBJECTIVES: Health promotion using web-based tools may provide some benefit to patients with diabetes mellitus. This meta-analysis assessed the effectiveness of web-based tools in improving blood glucose control.
METHODS: Randomized, controlled trials (web-based tools vs. usual care) were identified from research databases using the following criteria: participants were patients with diabetes (type 1 or 2) who had suboptimal blood glucose control (glycated hemoglobin [A1C] >7%), and outcomes included A1C. Two reviewers independently screened and extracted data. Study quality was evaluated based on randomization; concealment of allocation; blinding; accounting for dropouts and losses to follow-up; and overall quality based on the Grading of Recommendations Assessment, Development and Evaluation scale.
RESULTS: Nine studies were included. Pooled estimates showed a significant mean difference in A1C favouring web-based tools. The mean differences were -0.71% (95% CI -1.00, -0.43) after 3 months, -0.52% (95% CI -0.75, -0.29) after 6 months and -0.55% (95% CI -0.70, -0.39) after 12 months. There was heterogeneity among studies with 12 months of intervention (I(2)=78%). There was also a significant mean difference in low-density lipoprotein cholesterol (LDL-C) favouring web-based tools (-0.23 mmol/L, 95% CI -0.28, -0.19).
CONCLUSION: This study showed that web-based tools were better than usual care in improving A1C and LDL-C. Future studies should assess the cost benefit of web-based tools and further improve their effectiveness.

• 出版日期2011-9