Sox2, a marker for stem-like tumor cells in skin squamous cell carcinoma and hedgehog subgroup medulloblastoma

作者：Becher Oren J^*; Holland Eric C

来源：The EMBO Journal, 2014, 33(18): 1984-1986.

DOI：10.15252/embj.201489479

Heterogeneity within tumors is becoming increasingly recognized as an important cause of treatment failure in cancer. Two recent studies use fate-mapping and limiting dilution transplantation assays to identify SRY (sex determining region Y)-box 2 (Sox2) as cancer stem-cell marker and driver of cancer stemness.

• 出版日期2014-9-17