A one-pot catalyst-free synthesis of functionalized pyrrolo[1,2-a]quinoxaline derivatives from benzene-1,2-diamine, acetylenedicarboxylates and ethyl bromopyruvate

作者：Piltan Mohammad^*; Moradi Loghman; Abasi Golaleh; Zarei Seyed Amir

来源：Beilstein Journal of Organic Chemistry, 2013, 9: 510-515.

DOI：10.3762/bjoc.9.55

• acetylenedicarboxylates
• benzene-1,2-diamine
• ethyl bromopyruvate
• pyrrolo[1,2-a]pyrazine
• pyrrolo[1,2-a]quinoxaline

The catalyst-free multicomponent reaction of 1,2-diaminobenzene, dialkyl acetylenedicarboxylates, and ethyl bromopyruvate forms pyrrolo[1,2-a] quinoxaline derivatives in good yields. Ethylenediamine also reacts under similar conditions to produce new pyrrolo[1,2-a]pyrazine derivatives.

• 出版日期2013-3-11