Proteases in Fas-mediated apoptosis

作者：Zhivotovsky B; Burgess DH; Schlegel J; Porn MI; Vanags D; Orrenius S

来源：Journal of Cellular Biochemistry, 1997, 64(1): 43-49.

DOI：10.1002/(SICI)1097-4644(199701)64:1<43::AID-JCB7>3.0.CO;2-#

• apoptosis
• Fas
• proteases
• substrates

Involvement of a unique family of cysteine proteases in the multistep apoptotic process has been documented. Cloning of several mammalian genes identifies some components of this cellular response. However, it is currently unclear which protease plays a role as a signal and/or effector of apoptosis. We summarize contributions to the data concerning proteases in Fas-mediated apoptosis.

• 出版日期1997-1