A review of multisite pacing to achieve cardiac resynchronization therapy

作者:Rinaldi Christopher Aldo*; Burri Haran; Thibault Bernard; Curnis Antonio; Raos Archana; Gras Daniel; Sperzel Johannes; Singh Jagmeet P; Biffi Mauro; Bordachar Pierre; Leclercq Christophe
来源:Europace, 2015, 17(1): 7-17.
DOI:10.1093/europace/euu197

摘要

Non-response to cardiac resynchronization therapy remains a significant problem in up to 30% of patients. Multisite stimulation has emerged as a way of potentially overcoming non-response. This may be achieved by the use of multiple leads placed within the coronary sinus and its tributaries (dual-vein pacing) or more recently by the use of multipolar (quadripolar) left ventricular pacing leads which can deliver pacing stimuli at multiple sites within the same vein. This review covers the role of multisite pacing including the interaction with the underlying pathophysiology, the current and planned studies, and the potential pitfalls of this technology.