摘要

The therapy of cholangiocarcinoma is multimodal and includes systemic chemotherapy in addition to local palliative measures depending on the localization and the pattern of spreading. The effectiveness of 5-fluorouracil, gemcitabine and platinum analogues has been confirmed by several non-randomized studies. In a current large randomized phase III study the combination of gemcitabine and cisplatin significantly extended the average survival by 3.6 months compared to gemcitabine.

  • 出版日期2010-9

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