Anti-ageing activity of Fitchia nutans extract, a cosmeticeutical ingredient of a Polynesian traditional monoi

作者：Ansel Jean Luc; Ly Quoc; Butaud Jean Francois; Nicolas Mael; Herbette Gaetan; Peno Mazzarino Laurent; Lati Elian; Raharivelomanana Phila^*

来源：Comptes Rendus Chimie, 2016, 19(9): 1049-1055.

DOI：10.1016/j.crci.2016.03.005

• Fitchia nutans
• Anti-ageing activity
• Ex vivo human skin tests
• Collagen
• Elastin
• Costunolide
• Isovaleryl esters

Cosmetopea regards on Fitchia nutans (asteraceae), an endemic plant previously used as a skin care ingredient included in a sacred traditional monai preparation in French Polynesia, led us to investigate its cosmetoceutical properties. An extract of leaves of F. nutans was submitted to anti-ageing activity assays using ex vivo human skin tests and evidenced its potential to stimulate collagens and elastin dermal growth. We report herein the first phytochemical study of this plant extract, showing that its main constituents are sesquiterpenoids (including a new natural product compound: 15-isovaleroyloxydihydrocostunolide), phenylpropanoids, and phenolic derivatives.

• 出版日期2016-9