Application of alpha-chloroaldoxime O-methanesulfonates to one-pot synthesis of N,N ',N ''-substituted guanidines via Tiemann rearrangement

作者：Yamamoto Yuhei^*; Mizuno Hiroo; Tsuritani Takayuki; Mase Toshiaki

来源：Tetrahedron Letters, 2009, 50(42): 5813-5815.

DOI：10.1016/j.tetlet.2009.07.147

• Guanidines
• alpha-Chloroaldoxime O-methanesulfonates
• Tiemann rearrangement
• Carbodiimides

A practical one-pot synthesis of N,N',N ''-trisubstituted guanidines via Tiemann rearrangement involving the reaction of alpha-chloroaldoxime O-methanesulfonates with alkyl amines is disclosed.

• 出版日期2009-10-21