Iterative breakthrough invasive aspergillosis due to TR(34)/L98H azole-resistant Aspergillus fumigatus and Emericella sublata in a single hematopoietic stem cell transplant patient

作者：de Fontbrune F S; Denis B; Meunier M; Garcia Hermoso D; Bretagne S; Alanio A^*

来源：Transplant Infectious Disease, 2014, 16(4): 687-691.

DOI：10.1111/tid.12231

• invasive aspergillosis
• azole resistance
• breakthrough infection
• Aspergillus fumigatus
• Emericella sublata

We report 3 consecutive episodes of invasive aspergillosis in a single hematopoietic stem cell transplant patient successively attributed to TR(34)/L98H azole-resistant Aspergillus fumigatus and to a first occurrence of invasive Emericella sublata infection. This case illustrates potential selection of resistant molds during antifungal therapy in hematological patient.

• 出版日期2014-8