Asymmetric synthesis of multi-substituted triptycenes via enantioselective alkynylation of 1,5-dibromoanthracene-9,10-dione

作者：Shibata Takanori^*; Kamimura Yuri

来源：Tetrahedron: Asymmetry , 2015, 26(1): 41-45.

DOI：10.1016/j.tetasy.2014.11.012

Enantioselective alkynylation of 1,5-dibromoanthracene-9,10-dione by alkynyllithium reagents prepared from alkynes, n-BuLi, and sparteine gave chiral cis-diols possessing two alkyne moieties with moderate ee. Subsequent Ru-catalyzed [2+2+2] cycloaddition of the diol with alkynes afforded chiral 1,5-dibromotriptycenes.

• 出版日期2015-1-15