Annulation reaction of methyl 2-(benzo[b][1,4]thiazin-3-ylidene) acetate with beta-nitrostyrenes and 3-nitrochromenes

作者：Sun, Quan-Shun; Sun, Jing^*; Jiang, Wang; Yan, Chao-Guo^*

来源：Tetrahedron, 2018, 74(10): 1040-1046.

DOI：10.1016/j.tet.2018.01.027

• Domino reaction
• beta-enamino ester
• 2-Aminobenzenethiol
• 3-Nitrochromene
• benzo[b]pyrrolo[1,2-d][1,4]thiazine

The acid catalyzed domino reaction of beta-nitrostyrenes with methyl 2-(benzo[b][1,4]thiazin-3-ylidene) acetate, which were previously prepared from the cyclization of 2-aminobenzenethiol and methyl 4-chloroacetoacetate, resulted in 2-arylbenzo[b]pyrrolo[1,2-d][1,4]thiazine-3-carboxylates in high yields. Under same reaction conditions, the similar reaction with 3-nitrochromenes afforded corresponding benzo[b]chromeno[4',3':4,5]pyrrolo[1,2-d][1,4]thiazine derivatives in good yields.

• 出版日期2018-3-8
• 单位扬州大学