Aerobic photooxidative synthesis of 2-aryl-4-quinazolinones from aromatic aldehydes and aminobenzamide using catalytic amounts of molecular iodine

作者：Nagasawa Y; Matsusaki Y; Nobuta T; Tada N; Miura T; Itoh A^*

来源：RSC Advances, 2015, 5(78): 63952-63954.

DOI：10.1039/c5ra07275a

This study reports a safe, mild, and environmentally benign synthetic method toward 2-aryl-4-quinazolinones from aromatic aldehydes and aminobenzamides through a cyclization-oxidation sequence using a catalytic amount of iodine, which serves as both a Lewis acid and an oxidant, harmless visible light irradiation, and molecular oxygen as the terminal oxidant.

• 出版日期2015