Limitations in Clinical Translation of Nanoparticle-Based Gene Therapy

作者:Wong Joanna K L; Mohseni Rashin; Hamidieh Amir Ali; MacLaren Robert E; Habib Nagy; Seifalian Alexander M*
来源:Trends in Biotechnology, 2017, 35(12): 1124-1125.
DOI:10.1016/j.tibtech.2017.07.009

摘要

Organic nanoparticle-based (ONP) gene therapy is a potential strategy to cure human cancer. However, there are still many practical barriers before the promising results from in vitro and preclinical studies can be translated to clinical success. We discuss the reasons behind the hesitant uptake by the clinic.

  • 出版日期2017-12