A differentially selective probe based on diketopyrrolopyrrole with fluorescence turn-on response to Fe3+, and dual-mode turn-on and ratiometric response to Au3+, and its application in living cell imaging

作者：Yang, Xiaofeng^*; Liu, Xiaolei; Li, Yexin; Wu, Fan; Mao, Jiaxin; Yuan, Yuan; Cui, Yu^*; Sun, Guoxin^*; Zhang, Guangyou

来源：Biosensors and Bioelectronics, 2016, 80: 288-293.

DOI：10.1016/j.bios.2016.01.085

• Multiple-analyte recognition
• Au3+ ion
• Fe3+ ion
• "Turn-on" response
• Ratiometric response
• Bioimaging

A diketopyrrolopyrrole-based probe DPP-PyR was able to recognize Fe3+ and Au3+ with fluorescent turn-on response via different emission modes with relatively low detection limit. Moreover, DPP-PyR exhibited preferential second mode of selectivity for Au3+ as it ratiometrically displaced Fe3+ from the [DPP-PyR+Fe3+] complex. Furthermore, the imaging experiments indicated that this probe was cell permeable and could be used to detect Fe3+ and Au3+ ions within living cell. To the best of our knowledge, it was the first probe for detection Fe3+ and Au (3+) at the same time ever reported.

• 出版日期2016-6-15
• 单位济南大学