A Robust Synthesis of N-epsilon-(Carboxymethyl)-L-lysine (CML)

作者：Csuk Rene^*; Stark Sebastian; Barthel Alexander; Kluge Ralph; Stroehl Dieter

来源：Synthesis, 2009, 2009(11): 1933-1934.

DOI：10.1055/s-0028-1088064

• amino acids
• medicinal chemistry
• hydrogenation
• aminations
• reductions

N-epsilon-(Carboxymethyl)-L-lysine is easily obtained by reductive amination of glyoxylic acid with N-alpha-acetyl-L-lysine in the presence of a palladium catalyst and hydrogen.

• 出版日期2009-6-3