Uncommon 18F-FDG-PET/CT findings in patients affected by limbic encephalitis: hyper-hypometabolic pattern with double antibody positivity and migrating foci of hypermetabolism

作者：Cistaro Angelina^*; Caobelli Federico; Quartuccio Natale; Fania Piercarlo; Pagani Marco

来源：Clinical Imaging, 2015, 39(2): 329-333.

DOI：10.1016/j.clinimag.2014.09.004

• F-18-FDG PET/CT
• MRI
• Autoimmune limbic encephalitis
• GAD
• NMDAR

Autoimmune limbic encephalitis (LE) is a rare disorder; its diagnosis can be challenging. We report two uncommon cases of LE evaluated by brain 2-deoxy-2[18F]fluoro-d-glucose (F-18-FDG) positron emission tomography/computed tomography describing the metabolic imaging patterns, which were different from those observed in previous studies: the first one presented an unprecedented F-18-FDG brain mixed pattern, involving also the midbrain, despite negative magnetic resonance imaging exams; the second one showed migrating foci of hypermetabolism, one of which turned into hypometabolism at a later examination.

• 出版日期2015-4