Nanoparticles for Imaging, Sensing, and Therapeutic Intervention

作者:Bogart Lara K; Pourroy Genevieve; Murphy Catherine J; Puntes Victor; Pellegrino Teresa; Rosenblum Daniel; Peer Dan*; Levy Raphael
来源:ACS Nano, 2014, 8(4): 3107-3122.
DOI:10.1021/nn500962q

摘要

Nanoparticles have the potential to contribute to new modalities in molecular imaging and sensing as well as in therapeutic Interventions. In this Nano Focus article, we identify some of the current challenges and knowledge gaps that need to be confronted to accelerate the developments of various applications. Using specific examples, we journey from the characterization of these complex hybrid nanomaterials; continue with surface design and (bio)physicochemical properties, their fate in biological media and cells, and their potential for cancer treatment; and finally reflect on the role of animal models to predict their behavior in humans.

  • 出版日期2014-4