Automatic Alignment of Myocardial Perfusion Images With Contrast-Enhanced Cardiac Computed Tomography

作者：Faber Tracy L^*; Santana Cesar A; Piccinelli Marina; Nye Jonathon A; Votaw John R; Garcia Ernest V; Haber Eldad

来源：IEEE Transactions on Nuclear Science, 2011, 58(5): 2296-2302.

DOI：10.1109/TNS.2011.2163526

• Computer-aided diagnosis
• image registration
• nuclear medicine

Explicit fusion of perfusion data from Positron Emission Tomography (PET) or Single Photon Emission Computed Tomography (SPECT) with coronary artery anatomy from Computed Tomographic Coronary Angiography (CTA) has been shown to improve the diagnostic yield for coronary artery disease (CAD) compared to either modality alone. However, most clinically available methods were developed for multimodal scanners or require interactive alignment prior to display and analysis. A new approach was developed to register the two distributions obtained either from a single multimodal imager or from separate scanners, and a preliminary validation was undertaken to compare the automatic alignment to interactive alignment by two experts.

• 出版日期2011-10