Multiple Genes and Locus Interactions in Susceptibility to Vitiligo

作者:Smith Aaron G; Sturm Richard A*
来源:Journal of Investigative Dermatology, 2010, 130(3): 643-645.
DOI:10.1038/jid.2009.403

摘要

Refining the position of loci on chromosomes 7 and 9 previously linked with generalized vitiligo or vitiligo-associated autoimmune diseases presenting in families has been performed by high-density single-nucleotide polymorphism (SNP) genotyping. Investigation of the genetic interaction among these loci (and with a previously identified Susceptibility gene, NLRP1, on chromosome 17) as risk factors for vitiligo demonstrates the complex nature of this disease.

  • 出版日期2010-3