Dopant-Controlled Synthesis of Water-Soluble Hexagonal NaYF4 Nanorods with Efficient Upconversion Fluorescence for Multicolor Bioimaging

作者：Yu, Xuefeng; Li, Min; Xie, Mengyin; Chen, Liangdong; Li, Yan; Wang, Ququan^*

来源：Nano Research, 2010, 3(1): 51-60.

DOI：10.1007/s12274-010-1008-2

• Crystal growth
• hexagonal NaYF4
• nanocrystals
• fluorescence
• bioimaging

A novel strategy is proposed to directly synthesize water-soluble hexagonal NaYF4 nanorods by doping rare-earth ions with large ionic radius (such as La3+, Ce3+, Pr3+, Nd3+, Sm3+, Eu3+, and Gd3+), and the dopant-controlled growth mechanism is studied. Based on the doping effect, we fabricated water-soluble hexagonal NaYF4:(Yb, Er)/ La and NaYF4:(Yb, Er)/Ce nanorods, which exhibited much brighter upconversion fluorescence than the corresponding cubic forms. The sizes of the nanorods can be adjusted over a broad range by changing the dopant concentration and reaction time. Furthermore, we successfully demonstrated a novel depth-sensitive multicolor bioimaging for in vivo use by employing the as-synthesized NaYF4:(Yb, Er)/La nanorods as probes.

• 出版日期2010-1
• 单位武汉大学