Air-Stable Carbonyl(pentamethylcyclopentadienyl)cobalt Diiodide Complex as a Precursor for Cationic (Pentamethylcyclopentadienyl)cobalt(III) Catalysis: Application for Directed C-2 Selective C-H Amidation of Indoles

作者：Sun, Bo; Yoshino, Tatsuhiko; Matsunaga, Shigeki^*; Kanai, Motomu

来源：Advanced Synthesis & Catalysis, 2014, 356(7): 1491-1495.

DOI：10.1002/adsc.201301110

• catalysis
• C-H functionalization
• C-N bond formation
• cobalt
• indoles

The readily available carbonyl(pentamethylcyclopentadienyl)cobalt diiodide complex [Cp*Co(CO)I-2] was successfully utilized as the precursor of a cationic cobalt(III) active catalyst for directed CH bond functionalization. The complex Cp*Co(CO)I-2 (2.5-1.25mol%), in combination with silver hexafluoroantimonate (AgSbF6) and potassium acetate (KOAc), efficiently catalyzed the directed C-2 selective amidation of indoles with sulfonyl azides, and the corresponding products were obtained in 85-98% yield.

• 出版日期2014-5-5