Ultrasound-assisted Pechmann condensation of phenols with beta-ketoesters to form coumarins, in the presence of bismuth(III) chloride catalyst

作者：Patil SB; Bhat RP; Raje VP; Samant SD^*

来源：Synthetic Communications, 2006, 36(4): 525-531.

DOI：10.1080/00397910500385241

• bismuth(III) chloride (BiCl3)
• coumarins
• Pechmann condensation
• ultrasound

Ultrasound was found to synergistically accelerate the condensation of phenol with ss-ketoesters in the presence of BiCl3 . In the absence of ultrasound, under the same conditions, the reaction was found to be slow. Thus, the reaction can be carried out in the presence of ultrasound at room temperature (28-30 degrees C), with a considerable reduction of reaction time, with high yield and high purity of coumarins.

• 出版日期2006