Molecular identification and phylogenetic study of coxsackievirus A24 variant isolated from an outbreak of acute hemorrhagic conjunctivitis in India in 2010

作者：Shukla Deepti; Kumar Arvind; Srivastava Shalini; Dhole Tapan N^*

来源：Archives of Virology, 2013, 158(3): 679-684.

DOI：10.1007/s00705-012-1520-7

• Coxsackievirus A24
• Molecular identification
• VP1
• 3C
• Phylogenetic analysis

An outbreak of acute hemorrhagic conjunctivitis (AHC) occured in India between August and October 2010. Molecular typing by RT-PCR and sequencing of a partial VP1 region identified coxsackievirus A24 variant (CV A24v) as the serotype involved in this outbreak. Phylogenetic analysis based on the VP1 and 3C genes revealed that CV A24v strains associated with the 2010 AHC outbreak in India were genetically similar to strains from Central and South America that caused outbreaks of AHC in Cuba between 2008 and 2009 and Brazil in 2009. The result shows that the Indian strain of CV A24v may be responsible for the recent AHC outbreak in Marseille, France, in 2012.

• 出版日期2013-3
• 单位河北医科大学