Design of an Advanced Time-Domain Diffuse Optical Tomography System

作者：Mo Weirong^*; Chen Nanguang

来源：IEEE Journal of Selected Topics in Quantum Electronics, 2010, 16(3): 581-587.

DOI：10.1109/JSTQE.2009.2031617

• Optical control
• optical modulation
• optical time-domain reflectometry
• optical tomography

This paper describes the design of an improved multichannel time-domain diffuse optical tomography (TD-DOT) system. For the spread spectrum TD-DOT, the image quality depends on the stability of the time-resolved signals, which can be affected by fluctuation in the source modulation depth and drift in the detector gain. A microcontroller-based bias controller is designed to lock the bias of a Mach-Zehnder intensity modulator at the positive quadrature point. With additional temperature stabilization over the avalanche photodiodes, the temporal stability of the time-resolved signals has been significantly improved-the fluctuations of the temporal point spread function have been limited to +/-2% for a testing period of a few hours. The image quality and reproducibility have been substantially improved with the stabilized signals.

• 出版日期2010-6