科研之友
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摘要
A rhodamine-based water-soluble fluorescent probe of Fe3+(T1) was designed and synthesized, in which a carboxy was linked to enhance its water solubility. Its structure was characterized by H-1 NMR, C-13 NMR and HRMS-ESI. The fluorescent probe showed remarkable "turn-on" fluorescent responses to Fe3+ with good selectivity over other competitive cations. It has a good water solubility that the recognition properties of the probe with Fe3+ ions can be investigated in DMF/Tris-HCl (V:V=1:9, pH=7.4). The fluorescence imaging experiments of Fe3+ in MCF-7 living cells demonstrated that the probe had a good cell-membrane permeability and it could be used in biological systems.
- 出版日期2017-3-25
- 单位福建师范大学
