A biomimetic total synthesis of allomicrophyllone: protective Diels-Alder reaction as a stratagem

作者:Mehta Goverdhan*; Khan Tabrez Babu
来源:Tetrahedron Letters, 2010, 51(50): 6590-6593.
DOI:10.1016/j.tetlet.2010.10.063

摘要

A biomimetic total synthesis of bioactive tetracyclic natural product allomicrophyllone has been achieved in which a protective Diels-Alder reaction employing a disposable sacrificial 1,3-diene directs the regioselectivity of the subsequent Dials-Alder reaction.

  • 出版日期2010-12-15