Highly stereoselective approach toward the synthesis of the macrolactone core of amphidinolide W

作者：Mohapatra Debendra K^*; Chatterjee Bhaskar; Gurjar Mukund K

来源：Tetrahedron Letters, 2009, 50(7): 755-758.

DOI：10.1016/j.tetlet.2008.11.088

• Amphidinolide W
• Evans alkylation
• Evans aldol
• Julia-Kocienski olefination
• Kita's macrocyclization

The diastereoselective synthesis of the macrolactone core of amphidinolide W was successfully accomplished using Evans' asymmetric alkylation, Aldol reaction, Julia-Kocienski olefination, and Kita's macrocyclization protocol.

• 出版日期2009-2-18