Angiotensin Converting Enzyme and Dipeptidyl Peptidase-IV Inhibitory, and Antioxidant Activities of a Blue Mussel (Mytilus edulis) Meat Protein Extract and Its Hydrolysates

作者：Neves Adriana C; Harnedy Padraigin A; FitzGerald Richard J^*

来源：Journal of Aquatic Food Product Technology, 2016, 25(8): 1221-1233.

DOI：10.1080/10498850.2015.1051259

• Mussel meat
• hydrolysis
• angiotensin converting enzyme
• dipeptidyl peptidase-IV
• oxygen radical absorbance capacity

Protein extracted from mussel processing coproducts was hydrolyzed with four different food-grade enzyme preparations and assessed for angiotensin converting enzyme (ACE) and dipeptidyl peptidase-IV (DPP-IV) inhibitory and oxygen radical antioxidant capacity (ORAC) activities. All hydrolysates tested showed higher activity than the intact protein. ACE and DPP-IV IC50 values in the range 1.13-3.34 and 0.33-2.43 mg mL(-1), respectively, and ORAC values in the range 66.26-121.56 mu mol trolox equivalents g(-1) were obtained. These results suggest that some of the mussel meat protein hydrolysates may have potential as functional food ingredients for the management of diseases such as type II diabetes and hypertension.

• 出版日期2016