A new echocardiographic index for assessing left ventricular function and mechanism of mitral regurgitation and its relation to other echocardiographic indices

作者：Sag Cemal^*; Uzun Mehmet; Bolcal Cengiz; Yokusoglu Mehmet; Kucukarslan Nezihi; Koz Cem; Baysan Oben; Ozkan Mustafa; Karaeren Hayrettin; Genc Celal; Isik Ersoy

来源：Echocardiography-A Journal of Cardiovascular Ultrasound and Allied Techniques, 2007, 24(6): 561-566.

DOI：10.1111/j.1540-8175.2007.00432.x

• mitral regurgitation
• total dt
• left ventricular function

Objective: Mitral regurgitation (MR) is a progressive disease of the mitral valve, which can be primary or functional. The assessment of left ventricular function in MR is still troublesome. In this study, we evaluated the validity of a new parameter, total dt, in patients with MR. Methods: Forty patients with severe MR constituted the study group. According to the transesophageal echocardiographic evaluation, the patients were dichotomized into two groups: (1) Primary MR; n = 21, (2) Functional MR; n = 19. The total dt was defined as the sum of time intervals from 1 ms to 3 ms (positive dt) and from 3 ms to 1 ms (negative dt) on the CW Doppler recording of MR jet. It was compared to other indices of left ventricular function and left ventricular geometry, including ejection fraction, fractional shortening, myocardial performance index, coaptation distance, left ventricular volume and diameter, sphericity index, and parameters of diastolic function. Result: The total dt correlated with myocardial performance index, coaptation distance, and sphericity index. It could differentiate between primary and functional MR with an area under curve of 0.878, followed by myocardial performance index with 0.860. The total dt > 104 ms was 79% sensitive and 81% specific for discrimination. Conclusion: The total dt is useful for assessing left ventricular function and also for differentiating primary MR from functional MR.

• 出版日期2007-7
• 单位中国人民解放军军事医学科学院