New and efficient synthesis of 1,4-oxazines through the reaction of acetylenic esters and nitrosonaphthols in the presence of phosphine derivatives

作者：Mohebat Razieh^*; Abadi Afshin Yazdani Elah; Soltani Aliakbar; Saghafi Mitra

来源：ARKIVOC, 2016, 2016(4): 1-9.

DOI：10.3998/ark.5550190.p009.543

• Nitrosonaphthols
• acetylenic esters
• phosphine derivatives
• 1,4-oxazines
• intramolecular Wittig reaction

Protonation of the reactive 1:1 intermediate produced in the reaction between phosphine derivatives and dialkyl acetylenedicarboxylates with 1-nitroso-2-naphthol or 2-nitroso-1-naphthol leads to a vinylphosphonium salt which undergoes intramolecular Wittig reaction to produce 1,4-oxazine derivatives without any catalyst in good yields.

• 出版日期2016