Dipyrido[1,2-a;3 ',4 '-d]imidazole systems

作者:Cartwright Matthew W; Convery Laura; Kraynck Thomas; Sandford Graham*; Yufit Dmitrii S; Howard Judith A K; Christopher John A; Miller David D
来源:Tetrahedron, 2010, 66(2): 519-529.
DOI:10.1016/j.tet.2009.11.036

摘要

Novel tricyclic dipyridoimidazole derivatives can be readily synthesised in one pot processes from various highly fluorinated pyridine systems such as pentafluoropyridine and relatively nucleophilic 2-aminopyridine derivatives. Further nucleophilic aromatic substitution reactions of the novel tricyclic scaffolds allow the regioselective synthesis of various nitrogen, oxygen, carbon and sulfur-functionalised dipyridoimidazole products.

  • 出版日期2010-1-9