Long noncoding RNAs in psychiatric disorders

作者：Zuo, Lingjun; Tan, Yunlong; Wang, Zhiren; Wang, Ke Sheng; Zhang, Xiangyang; Chen, Xiangning; Li, Chiang Shan R; Wang, Tong; Luo, Xingguang^*

来源：Psychiatric Genetics, 2016, 26(3): 109-116.

DOI：10.1097/YPG.0000000000000129

• lncRNAs
• psychiatric disorders
• regulation

Long noncoding RNAs (lncRNAs) are nonprotein coding transcripts longer than 200 nucleotides. Many of these lncRNAs have regulatory functions and have recently emerged as major players in governing fundamental biological processes. Here, we review the definition, distribution, identification, databases, analysis, classification, and functions of lncRNAs. We also discuss the potential roles of lncRNAs in the etiological processes of psychiatric disorders and the implications for clinical diagnosis and treatment.

• 出版日期2016-6
• 单位北京回龙观医院