An Overview of Currently Available Antimalarials

作者:Gorobets Nikolay Yu*; Sedash Yuriy V; Singh Brajendra K; Poonam; Rathi Brijesh*
来源:Current Topics in Medicinal Chemistry, 2017, 17(19): 2143-2157.
DOI:10.2174/1568026617666170130123520

摘要

Background: Despite the substantial progress over the time, malaria remains a major public health concern and causing hundreds of thousands of deaths. Resistance to the available antimalarial therapy increases threat to the global public health. Objective: Overview of currently available antimalarials. Method: Literary survey. Results: The summarized data about different types of antimalarial therapies and their efficiency and modes of action. Conclusion: Despite the seemingly large number of the drugs currently available for malaria treatment, this arsenal is limited due to the narrow variation of their mechanism of action.

  • 出版日期2017