Alternative Plugs Flow Liquid Chromatography (APFLC)/EI-MS System Using a T-shaped Flow Path

作者：Tanikawa Isao^*; Konuma Miwako; Hosono Hiroko; Nakamura Hiroshi

来源：Analytical Sciences, 2011, 27(1): 95-99.

DOI：10.2116/analsci.27.95

The vapor condensation method can be used for forming an alternative flow of liquid masses using a single solvent for alternative plugs flow liquid chromatography (APFLC), described in our previous paper. APFLC is more effective when adopting a T-shaped flow path and aqueous-organic solvents with a liquid-to-gas volume ratio (bulk fraction; beta) ranging between 0.0006 and 0.004 in an open tubular GC capillary column at below 70 degrees C. High-density plugs flow by a T-shaped flow path leads to extremely high resolution. Alternative plugs flow is formed when the liquid contact angle to the solid phase is above 75 degrees. An aqueous mixture of the usual HPLC solvent can be readily used for APFLC. An EI-mass spectrum is obtained that is comparable with that in the NIST library, except for the DMF mixture medium. Due to low-pressure loss properties in the column, the system does not require a high-pressure liquid pump. Solid hydrocarbon resin with a contact angle to water of between 75 degrees and 79 degrees, such as polystyrene and olefinic polymers, is anticipated to be applicable to APFLC and hydro-membrane gas chromatography (HMGC) by a consideration of their surface tensions.

• 出版日期2011-1