科研之友
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摘要
Objective: Eustachian tube dysfunction (ETD) affects approximately 1% of adults in the general population. Non treated Eustachian tube dysfunction can result in chronic middle ear diseases, which have been shown to significantly affect taste sensitivity. A promising treatment is balloon dilatation of the Eustachian tube. The primary aim of the present study was to investigate whether individuals with ETD had impairment in chemosensory functions, and the changes of the chemosensory function after balloon dilatation of the Eustachian tube.
Methods: 26 patients (17 female, 9 male) (=56 ears) suffering from ETD with a mean age of 39 15 years were included in the present study. 20 patients (76%) returned to be evaluated at the follow up (=40 ears) 51 +/- 22 days after balloon dilatation. For pre- and post operation, gustatory function was measured with a lateralized gustatory test with the taste strips and olfactory function was tested by means of the Sniffin' Sticks test battery (threshold, discrimination and identification (ID)).
Results: Patients' baseline taste function (summed taste score 9.8 +/- 3.5 (mean SD)) was significantly impaired compared to normative data (summed taste score 12.4 +/- 2.3; p = 0.002). After balloon dilatation of the Eustachian tube, the taste function remained stable (summed taste score 9.4 +/- 4.3; p = 0.814). Olfactory function (odor ID, summed score (TDI)) improved postoperatively (TDI 32.4 +/- 3.6) compared to pre-operative scores (TDI 33.6 +/- 4.0; p = 0.012), but not to a clinically relevant extent.
Conclusion: This study suggests, that patients suffering from ETD exhibit reduced taste scores. Balloon dilatation of the Eustachian tube does not seem to influence gustatory function, but olfactory function showed improvement.
- 出版日期2018-10
- 单位河北医科大学
