Adhesion of L929 Mouse Fibroblast Cells on Poly(Styrene)/Poly(Methyl Methacrylate) Films

作者：de Melo Adriana; Bet Angela Cristina; Assreuy Jamil; Debacher Nito Angelo; Soldi Valdir^*

来源：Journal of the Brazilian Chemical Society, 2009, 20(9): 1753-1757.

• poly(styrene)
• poly(methyl metacrylate)
• block copolymer
• cell adhesion
• cytotoxicity

Films of pure poly(styrene) (PS), pure poly(methyl methacrylate) (PMMA), a 1: 1 PS/PMMA blend and a PS-b-PMMA copolymer, were prepared and tested for cell adhesion using L929 mouse fibroblasts. All polymer films were found to be good substrates for cell adhesion and proliferation, and both processes were slightly favored on films of the 1: 1 PS/PMMA blend. The same results were obtained in terms of cell number and morphology for cells cultured on films, glass coverslips or plastic plates. The chemical characteristics of polymer films make them suitable supports for cell attachment and proliferation, indicating that these films are good candidates for biomedical uses.

• 出版日期2009