Use of umbilical cord and cord blood-derived stem cells for tissue repair and regeneration

作者：Biazar Esmaeil^*

来源：Expert Opinion on Biological Therapy, 2014, 14(3): 301-310.

DOI：10.1517/14712598.2014.867943

• in vivo
• stem cells
• tissue repair and regeneration
• umbilical cord

Introduction: Potential use of umbilical cord (UC) is one of the most exciting frontiers in medicine for repairing damaged tissues. UC and cord blood-derived stem cells are the world's largest potential sources of stem cells. UC contains a mixture of stem and progenitor cells at different lineage commitment stages and UC has been verified as a candidate for cell-based therapies and tissue engineering applications due to the capability of these cells for extensive self-renewal and multi-lineage character in differentiation potential.
Areas covered: UC-based repair or regeneration of organs (i.e., heart, nerve, skin, etc.) is a high-priority research worldwide.
Expert opinion: The aim of this review is to summarize the knowledge about UC with main focus on its applications for tissue repair and regeneration.

• 出版日期2014-3