Application of high frequency bipolar electrocoagulation LigaSure (TM) in appendix vermiformis of rabbits with or without acute inflammatory process

作者：de Souza Laura Cristina; Ortega Maira Rocha; Achar Eduardo; Netto Dante Simionato; Fontenelle Ribeiro Junior Marcelo Augusto

来源：Acta Cirurgica Brasileira, 2012, 27(5): 322-329.

• Appendicitis
• Appendectomy
• Animal Experimentation
• Ligation
• Electrocoagulation
• Rabbits

PURPOSE: To evaluate the efficacy of the use of LigaSure (TM) in appendectomy, with or without acute inflammatory process, and to compare with simple ligature and conventional therapy.
METHODS: A total of 30 rabbits (Oryctolagus cuniculus) randomly allocated in two groups, group A and B, of 15 animals each were used. The group A without acute appendicitis and the group B with acute appendicitis were submitted to appendectomy. After, the groups were subdivided into three groups, each group containing five rabbits submitted to simple ligature, conventional therapy and application of LigaSure (TM). We assessed macroscopic and microscopy parameters of appendiceal stump and operative wound.
RESULTS: The group with acute appendicitis that LigaSure (TM) was applied had fibrosis in 100% of animals, as well as in the other operative techniques used. It suggested that application of LigaSure (TM) is efficient as other techniques used in healing of appendiceal stump.
CONCLUSIONS: The application of LigaSure (TM) induces the formation of fibrosis in the appendiceal stump. The technique proved efficacy to induce enough fibrous tissue to obstruct leakage of enteric content.

• 出版日期2012-5